Medical Publication Design

Net Prolongation of Life

The Paradigm Shift—LVAD to Heart Transplant

Designing the visual argument for a peer-reviewed clinical publication that reframes how cardiologists evaluate LVAD therapy versus heart transplantation—transforming dense registry data into a navigable, evidence-based narrative across a 40+ slide system, interactive clinical tools, and cohesive motion design.

Publication Design Data Visualization Interactive Tools Medical Communications Motion Design

Designing Clinical Advocacy

The HeartMate 3 has fundamentally changed outcomes for patients with end-stage heart failure—but the clinical community's assumptions haven't caught up. The data existed. The narrative didn't. We were brought in to build a visual system that could carry a 40+ slide argument from historical context through survival analysis to policy implications, all in service of a manuscript headed for peer review in the Journal of Heart and Lung Transplantation.

The core design challenge was credibility at scale: monospace typography anchored in data precision, dithered medical illustrations that gave clinical imagery texture without clinical coldness, and a deliberate cinematic framing—a 42-year-old mother with end-stage heart failure—that humanized the statistics without sentimentalizing them. Every chart was reverse-engineered from registry data and rebuilt as fully editable, publication-grade figures.

43
Designed slides spanning historical analysis, survival data, risk factors, and future outlook
15,000+
Patient records from INTERMACS, IMACS, and ELEVATE registries visualized across age, race, and risk strata
81%
One-year survival for LVAD patients aged 65+—the central finding the visual system was built to communicate

The Presentation System

Patient scenario—a 42-year-old mother with end-stage heart failure
Heart transplant survival—the current gold standard
Historical analysis—transplant or LVAD timeline
HeartMate 3—a longitudinal look into LVAD advancements
HM3 validated across multiple registries
HeartMate 3—the great equalizer across risk factors
LVAD Recovery Score—Interactive Calculator

LVAD Recovery Score Calculator

Beyond the presentation, we designed and built a fully interactive clinical tool—a multicenter recovery score calculator based on the HM3 Heart Registry (1,000+ patients, 118 centers). Clinicians input patient-specific variables—cardiomyopathy type, sex, heart failure duration, preoperative echo measurements—and receive a personalized probability of cardiac reverse remodeling during LVAD support.

The calculator transforms a logistic regression model from published literature into something a physician can use at the point of care. Not a slide. A working tool.

Try the Calculator

Beyond the Data

Myocardial recovery—an additional pathway
Quality of life—patient perspectives
The ideal durable MCS device
Patient-device interface refinement
Conclusions

Net Prolongation of Life with Durable Left Ventricular Assist Devices Compared with Listing for Heart Transplantation

Journal of Heart and Lung Transplantation—Uriel et al., 2026

This presentation system was designed to accompany and visually represent the findings of a peer-reviewed manuscript analyzing propensity-matched survival outcomes for LVAD versus heart transplant listing across age strata. The design work stands alongside published science—every chart, figure, and visual argument traces back to registry data cited in the paper.

Read the publication