Medical Publication Design

Net Prolongation of Life

The Paradigm Shift — LVAD to Heart Transplant

Designing the visual argument for a peer-reviewed clinical publication that reframes how cardiologists evaluate LVAD therapy versus heart transplantation — transforming dense registry data into a navigable, evidence-based narrative across a 40+ slide system, interactive clinical tools, and cohesive motion design.

Publication Design Data Visualization Interactive Tools Medical Communications Motion Design

Designing Clinical Advocacy

The HeartMate 3 has fundamentally changed outcomes for patients with end-stage heart failure — but the clinical community's assumptions haven't caught up. The data existed. The narrative didn't. We were brought in to build a visual system that could carry a 40+ slide argument from historical context through survival analysis to policy implications, all in service of a manuscript headed for peer review in the Journal of Heart and Lung Transplantation.

The core design challenge was credibility at scale: monospace typography anchored in data precision, dithered medical illustrations that gave clinical imagery texture without clinical coldness, and a deliberate cinematic framing — a 42-year-old mother with end-stage heart failure — that humanized the statistics without sentimentalizing them. Every chart was reverse-engineered from registry data and rebuilt as fully editable, publication-grade figures.

43
Designed slides spanning historical analysis, survival data, risk factors, and future outlook
15,000+
Patient records from INTERMACS, IMACS, and ELEVATE registries visualized across age, race, and risk strata
81%
One-year survival for LVAD patients aged 65+ — the central finding the visual system was built to communicate

The Presentation System

Patient scenario — a 42-year-old mother with end-stage heart failure
Heart transplant survival — the current gold standard
Historical analysis — transplant or LVAD timeline
HeartMate 3 — a longitudinal look into LVAD advancements
HM3 validated across multiple registries
HeartMate 3 — the great equalizer across risk factors
LVAD Recovery Score — Interactive Calculator

LVAD Recovery Score Calculator

Beyond the presentation, we designed and built a fully interactive clinical tool — a multicenter recovery score calculator based on the HM3 Heart Registry (1,000+ patients, 118 centers). Clinicians input patient-specific variables — cardiomyopathy type, sex, heart failure duration, preoperative echo measurements — and receive a personalized probability of cardiac reverse remodeling during LVAD support.

The calculator transforms a logistic regression model from published literature into something a physician can use at the point of care. Not a slide. A working tool.

Try the Calculator

Beyond the Data

Myocardial recovery — an additional pathway
Quality of life — patient perspectives
The ideal durable MCS device
Patient-device interface refinement
Conclusions

Net Prolongation of Life with Durable Left Ventricular Assist Devices Compared with Listing for Heart Transplantation

Journal of Heart and Lung Transplantation — Uriel et al., 2026

This presentation system was designed to accompany and visually represent the findings of a peer-reviewed manuscript analyzing propensity-matched survival outcomes for LVAD versus heart transplant listing across age strata. The design work stands alongside published science — every chart, figure, and visual argument traces back to registry data cited in the paper.

Read the publication